DETAILLIERTE HINWEISE ZUR BEHANDLUNG VON OPIOIDSUCHT

Patients should be cautioned that methadone, like other opioids, may produce orthostatic hypotension in ambulatory patients.Methadone should be given with caution and the initial dose reduced rein certain patients, such as the elderly and debilitated and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, p